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Izigaba Zemikhiqizo
Imikhiqizo efakiwe
01
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC
Ibanga lezemithi HPMC

Ibanga lezemithi HPMC

I-HPMC Hydroxypropyl methylcellulose imhlophe noma i-milky methylcellulose imhlophe noma i-milky, ayinaphunga, ayinambitheki, impushana ene-fibrous noma i-granule, ukwehla kwesisindo lapho isomiswa akudluli u-10%, kuncibilika emanzini abandayo kodwa hhayi emanzini ashisayo, kancane kancane emanzini ashisayo Ukuvuvuka, ukupepthiza, nokwenza isixazululo se-viscous colloidal, esiba yisixazululo lapho sipholile, futhi sibe ijeli lapho sishiswa.


I-Pharmaceutical Grade Hydroxypropyl Methylcellulose (HPMC) iwuhlobo olukhethekile lwe-HPMC olusetshenziswa embonini yezemithi. I-HPMC iyi-polymer encibilika emanzini etholakala ku-cellulose, futhi uma isetshenziswa ekwenziweni kwemithi, inikeza izinzuzo nezinhlelo zokusebenza ezimbalwa ezibalulekile.

    Xhumana nathi
    imininingwane yomkhiqizo

    Ukucaciswa Kwekhemikhali

    incazelo2

    Ukucaciswa

    I-HPMC 60

    ( 2910 )

    I-HPMC 65

    ( 2906 )

    I-HPMC 75

    ( 2208 )

    Izinga lokushisa lejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    I-Viscosity(cps, 2% Solution)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Ibanga Lomkhiqizo:

    incazelo2

    Ukucaciswa

    I-HPMC 60

    ( 2910 )

    I-HPMC 65

    ( 2906 )

    I-HPMC 75

    ( 2208 )

    Izinga lokushisa lejeli (℃)

    58-64

    62-68

    70-90

    I-Methoxy (WT%)

    28.0-30.0

    27.0-30.0

    19.0-24.0

    I-Hydroxypropoxy (WT%)

    7.0-12.0

    4.0-7.5

    4.0-12.0

    I-Viscosity(cps, 2% Solution)

    3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

    Isicelo

    incazelo2

    Isicelo se-Pharma Excipients

    Ibanga Lezemithi HPMC

    Umthamo

    I-Bulk Laxative

    75K4000,75K100000

    3-30%

    Amakhilimu, amaGel

    60E4000,75K4000

    1-5%

    Ukulungiselela Ophthalmic

    60E4000

    01.-0.5%

    Eye Drop Amalungiselelo

    60E4000

    0.1-0.5%

    Umenzeli Omisiwe

    60E4000, 75K4000

    1-2%

    Ama-Antacids

    60E4000, 75K4000

    1-2%

    I-Tablet Binder

    60E5, 60E15

    0.5-5%

    Umhlangano Wet Granulation

    60E5, 60E15

    2-6%

    I-Tablet Coatings

    60E5, 60E15

    0.5-5%

    I-Matrix yokukhishwa elawulwayo

    75K100000,75K15000

    20-55%

    imikhiqizo (1)ix8

    imikhiqizo (2)8x

    Izakhiwo Ezibalulekile Nokusetshenziswa Kwebanga Lezemithi i-HPMC:

    incazelo2

    1. Isibopho:

    I-HPMC isebenza njengesihlanganisi ekwakhiweni kwethebulethi yezemithi. Isiza ukubamba izithako zemithi esebenzayo (ama-APIs) kanye nezinsiza ndawonye ukuze kwakhe ithebhulethi ehlangene engangenwa kalula.

    2. I-Disintegrant:

    Kwezinye izimo, i-HPMC ingasetshenziswa njenge-disintegrant kumaphilisi. Isiza ekuqhekekeni okusheshayo kwethebhulethi ibe yizinhlayiya ezincane, okuvumela ukukhululwa nokumuncwa komuthi ohlelweni lokugaya ukudla.

    3. Izinto Zokuhlanganisa:

    I-HPMC isetshenziswa njengento yokumboza ifilimu yamaphilisi namaphilisi, ihlinzeka ngokuvikeleka kwesidakamizwa, ithuthukise ukufihla ukunambitheka, nokulawula ukukhishwa kwe-API.

    4. Ukukhishwa Okuqhubekayo:

    Ekwakheni okukhishwayo okulawulwayo, i-HPMC ingaqashwa ukulungisa ukukhishwa komuthi ngokuhamba kwesikhathi, inikeze umphumela wokwelapha omude.

    5. Isilungisi se-Viscosity:

    Isebenza njengesiguquli se-viscosity ekwakhiweni okuwuketshezi kanye ne-semi-solid, njengokumiswa komlomo nama-topical gels, ukulawula ukufana nokugeleza kwezakhiwo.

    6. I-Gelling Agent:

    I-HPMC ingasetshenziswa njenge-ejenti yokugaya ekwakhiweni kwamajeli omlomo kanye nama-mucilages ukuze kube lula ukulawula.

    Izicelo ze-Pharmaceutical Grade HPMC:

    incazelo2

    I-Pharmaceutical Grade HPMC isetshenziswa kabanzi kumafomu emithamo ehlukahlukene yemithi, okuhlanganisa:

    1. Amaphilisi:

    Iyingxenye ebalulekile ekwakhiweni kwethebhulethi, eqinisekisa ukubophezela okufanele kwezithako nezici zokuhlakazeka.

    2. Amaphilisi:

    I-HPMC ingasetshenziselwa ukwakheka kwama-capsule, kokubili njengesibophezelo sokugcwaliswa kwempushana nanjengengxenye yegobolondo lekhepisi lokulibaziseka noma ukukhululwa okuqhubekayo.

    3. Amathebulethi Amboziwe:

    Izembozo zefilimu ezenziwe nge-HPMC zivikela ithebhulethi futhi zilawule ukukhishwa komuthi.

    4. Ukumiswa Komlomo:

    Ekwakheni uketshezi, i-HPMC ingasebenza njengesishintshi se-viscosity, iqinise ukumiswa.

    5. Ama-Topical Gels nama-Cream:

    Isetshenziswa ekwakhiweni kwe-topical ukufeza ukuthungwa okufunayo nokuvumelana.

    6. Amafinyila:

    I-HPMC ingasetshenziswa ekwakheni ama-mucilages okuphathwa ngomlomo.

    Izinzuzo Zokusebenzisa Ibanga Lezemithi i-HPMC:

    incazelo2

    - Ukubopha okuthuthukisiwe kwethebhulethi nokuhlakazeka.
    - Ukukhululwa okulawulwayo kwezidakamizwa zemiphumela yokwelapha enwetshiwe.
    - Ukunambitha ukufihla ubuso nokuvikelwa komuthi kumaphilisi aboshwe.
    - Ukuthungwa okuthuthukisiwe nokuvumelana ekwakhekeni okuwuketshezi nokuqinile.
    - Ifanele ukusetshenziswa ezinhlobonhlobo zemithamo yemithi.

    I-Pharmaceutical Grade HPMC idlala indima ebalulekile embonini yezemithi, ibe neqhaza kwikhwalithi nokusebenza kokwenziwa kwemithi ehlukahlukene. Izakhiwo zayo ziyenza ibe isakhi esiguquguqukayo nesisetshenziswa kakhulu ekukhiqizweni kwamathebulethi, ekwenziweni kokukhishwa okulawulwayo, nakwezinye izinhlelo zemithi, iqinisekisa ukuthi imithi iyasebenza, izinzile, futhi iphephile ezigulini.

    Ukupakisha

    incazelo2

    Ukupakishwa okujwayelekile kungu-25kg/Fibre drum
    I-20'FCL: amathani ayi-9 ane-palletized; 10 ton unpalleted.
    I-40'FCL: amathani ayi-18 ane-palletized; 20 amathani unpalleted.

    Isitoreji:

    incazelo2

    Yigcine endaweni epholile, eyomile engaphansi kuka-30 ° C futhi ivikelwe ekumswakama nokucindezela, njengoba impahla i-thermoplastic, isikhathi sokugcina akufanele sidlule izinyanga ezingu-36.

    Amanothi okuphepha:

    incazelo2

    Idatha engenhla ihambisana nolwazi lwethu, kodwa ungawakhululi amaklayenti ngokuyibheka ngokucophelela yonke into ngokushesha lapho ithola. Ukuze ugweme ukwakheka okuhlukile nezinto zokusetshenziswa ezihlukile, sicela wenze ukuhlola okwengeziwe ngaphambi kokuzisebenzisa.